6BH3: LINKED KDM5A JMJ DOMAIN BOUND TO THE INHIBITOR (S)-N-(1-(3-isopropyl-1H-pyrazole-5-carbonyl)pyrrolidin-3-yl)cyclopropanecarboxamide (Compound N55)

PDB ID: 6BH3Download
MMDB ID: 160604
PDB Deposition Date: 2017/10/29
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 1.701  Å
Source Organism:
Similar Structures:
Biological Unit for 6BH3: monomeric; determined by author
Molecular Components in 6BH3
Label Count Molecule
Protein (1 molecule)
1
Lysine-specific Demethylase 5A, Linked Kdm5a JMJ Domain
(Gene symbol: KDM5A)
Molecule annotation
Chemicals and Non-standard biopolymers (10 molecules)
1
1
N-{(3S)-1-[5-(propan-2-yl)-1H-pyrazole-3-carbonyl]pyrrolidin-3-yl}cyclopropanecarboxamideN-{(3S)-1-[5-(propan-2-yl)-1H-pyrazole-3-carbonyl]pyrrolidin-3-yl}cyclopropanecarboxamide
2
1
MANGANESE (II) IONMANGANESE (II) ION
3
1
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
4
2
GLYCEROLGLYCEROL
5
5
1,2-ETHANEDIOL1,2-ETHANEDIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303