6DQ7: LINKED KDM5A JMJ DOMAIN BOUND TO THE POTENTIAL HYDROLYSIS PRODUCT OF INHIBITOR N45 i.e. 3-((6-(4-(2-cyano-3-methylbut-2-enoyl)-1,4-diazepan-1-yl)-2-(pyridin-2-yl)pyrimidin-4-yl)amino)propanoic acid

PDB ID: 6DQ7Download
MMDB ID: 176011
PDB Deposition Date: 2018/6/10
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 1.852  Å
Source Organism:
Similar Structures:
Biological Unit for 6DQ7: monomeric; determined by author and by software (PISA)
Molecular Components in 6DQ7
Label Count Molecule
Protein (1 molecule)
1
Linked Kdm5a JMJ Domain
(Gene symbol: KDM5A)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
1
N-{6-[4-(hydroxyacetyl)-1,4-diazepan-1-yl]-2-(pyridin-2-yl)pyrimidin-4-yl}-beta-alanineN-{6-[4-(hydroxyacetyl)-1,4-diazepan-1-yl]-2-(pyridin-2-yl)pyrimidin-4-yl}-beta-alanine
2
1
MANGANESE (II) IONMANGANESE (II) ION
3
1
1,2-ETHANEDIOL1,2-ETHANEDIOL
4
1
GLYCEROLGLYCEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303