6DQA: Linked KDM5A JMJ Domain Bound to Inhibitor N70 i.e.[2-((3-aminophenyl)(2-(piperidin-1-yl)ethoxy)methyl)thieno[3,2-b]pyridine-7-carboxylic acid]

PDB ID: 6DQADownload
MMDB ID: 168900
PDB Deposition Date: 2018/6/10
Updated in MMDB: 2018/11
Experimental Method:
x-ray diffraction
Resolution: 1.888  Å
Source Organism:
Similar Structures:
Biological Unit for 6DQA: monomeric; determined by author and by software (PISA)
Molecular Components in 6DQA
Label Count Molecule
Protein (1 molecule)
1
Linked Kdm5a JMJ Domain
(Gene symbol: KDM5A)
Molecule annotation
Chemicals and Non-standard biopolymers (7 molecules)
1
1
2-{(R)-(3-aminophenyl)[2-(piperidin-1-yl)ethoxy]methyl}thieno[3,2-b]pyridine-7-carboxylic acid2-{(R)-(3-aminophenyl)[2-(piperidin-1-yl)ethoxy]methyl}thieno[3,2-b]pyridine-7-carboxylic acid
2
1
MANGANESE (II) IONMANGANESE (II) ION
3
2
GLYCEROLGLYCEROL
4
3
1,2-ETHANEDIOL1,2-ETHANEDIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303