6DQE: LINKED KDM5A JMJ DOMAIN BOUND TO THE INHIBITOR N67 i.e. 2-(5-phenyl-4-(phenyl(2-(piperidin-1-yl)ethoxy)methyl)-1H-pyrazol-1-yl)isonicotinic acid

PDB ID: 6DQEDownload
MMDB ID: 176014
PDB Deposition Date: 2018/6/10
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 1.689  Å
Source Organism:
Similar Structures:
Biological Unit for 6DQE: monomeric; determined by author
Molecular Components in 6DQE
Label Count Molecule
Protein (1 molecule)
1
Linked Kdm5a JMJ Domain
(Gene symbol: KDM5A)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
1
2-(5-phenyl-4-{(R)-phenyl[2-(piperidin-1-yl)ethoxy]methyl}-1H-pyrazol-1-yl)pyridine-4-carboxylic acid2-(5-phenyl-4-{(R)-phenyl[2-(piperidin-1-yl)ethoxy]methyl}-1H-pyrazol-1-yl)pyridine-4-carboxylic acid
2
1
MANGANESE (II) IONMANGANESE (II) ION
3
1
GLYCEROLGLYCEROL
4
3
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303