6H7Y: X-ray structure of human glutamate carboxypeptidase II (GCPII) in complex with a inhibitor RNA 1-79-1

PDB ID: 6H7YDownload
MMDB ID: 169339
PDB Deposition Date: 2018/7/31
Updated in MMDB: 2018/12
Experimental Method:
x-ray diffraction
Resolution: 1.81  Å
Source Organism:
Similar Structures:
Biological Unit for 6H7Y: dimeric; determined by author
Molecular Components in 6H7Y
Label Count Molecule
Proteins (2 molecules)
2
Glutamate Carboxypeptidase 2
(Gene symbol: FOLH1)
Molecule annotation
Chemicals and Non-standard biopolymers (58 molecules)
1
20
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
3
beta-D-mannopyranosebeta-D-mannopyranose
3
3
alpha-D-mannopyranosealpha-D-mannopyranose
4
4
ZINC IONZINC ION
5
2
CALCIUM IONCALCIUM ION
6
4
CHLORIDE IONCHLORIDE ION
7
8
1,2-ETHANEDIOL1,2-ETHANEDIOL
8
4
TRIS(HYDROXYETHYL)AMINOMETHANETRIS(HYDROXYETHYL)AMINOMETHANE
9
6
DI(HYDROXYETHYL)ETHERDI(HYDROXYETHYL)ETHER
10
2
TRIETHYLENE GLYCOLTRIETHYLENE GLYCOL
11
2
(2~{S})-2-[[(2~{S})-6-[(4-fluorophenyl)amino]-1-oxidanyl-1,6-bis(oxidanylidene)hexan-2-yl]carbamoylamino]pentanedioic acid(2~{S})-2-[[(2~{S})-6-[(4-fluorophenyl)amino]-1-oxidanyl-1,6-bis(oxidanylidene)hexan-2-yl]carbamoylamino]pentanedioic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303