6JX4: Crystal structure of EGFR 696-1022 T790M in complex with AZD9291 prepared by soaking

PDB ID: 6JX4Download
MMDB ID: 186655
PDB Deposition Date: 2019/4/22
Updated in MMDB: 2024/11
Experimental Method:
x-ray diffraction
Resolution: 2.531  Å
Source Organism:
Similar Structures:
Biological Unit for 6JX4: monomeric; determined by author
Molecular Components in 6JX4
Label Count Molecule
Protein (1 molecule)
1
Epidermal Growth Factor Receptor
(Gene symbol: EGFR)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
N-(2-{[2-(dimethylamino)ethyl](methyl)amino}-4-methoxy-5-{[4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl]amino}phenyl)prop-2-enamide (Link to PubChem not yet available)N-(2-{[2-(dimethylamino)ethyl](methyl)amino}-4-methoxy-5-{[4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl]amino}phenyl)prop-2-enamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303