6K9V: Crystal structure of tubulin in complex with inhibitor D64

PDB ID: 6K9VDownload
MMDB ID: 178892
PDB Deposition Date: 2019/6/18
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 2.543  Å
Source Organism:
Rattus norvegicus▼
Similar Structures:
Biological Unit for 6K9V: hexameric; determined by author and by software (PISA)
Molecular Components in 6K9V
Label Count Molecule
Proteins (6 molecules)
2
Tubulin Alpha-1b Chain
Molecule annotation
2
Tubulin Beta-2b Chain
Molecule annotation
1
Stathmin-4
Molecule annotation
1
Tubulin Tyrosine Ligase
Molecule annotation
Chemicals and Non-standard biopolymers (14 molecules)
1
3
GUANOSINE-5'-TRIPHOSPHATEGUANOSINE-5'-TRIPHOSPHATE
2
5
MAGNESIUM IONMAGNESIUM ION
3
1
GUANOSINE-5'-DIPHOSPHATEGUANOSINE-5'-DIPHOSPHATE
4
1
2-(N-MORPHOLINO)-ETHANESULFONIC ACID2-(N-MORPHOLINO)-ETHANESULFONIC ACID
5
2
(5-methoxy-1H-indol-2-yl)-phenyl-methanone(5-methoxy-1H-indol-2-yl)-phenyl-methanone
6
1
CALCIUM IONCALCIUM ION
7
1
PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTERPHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303