6NTS: Protein Phosphatase 2A (Aalpha-B56alpha-Calpha) holoenzyme in complex with a Small Molecule Activator of PP2A (SMAP)

PDB ID: 6NTSDownload
MMDB ID: 187177
PDB Deposition Date: 2019/1/30
Updated in MMDB: 2023/11
Experimental Method:
electron microscopy
Resolution: 3.63  Å
Source Organism:
Similar Structures:
Biological Unit for 6NTS: trimeric; determined by author
Molecular Components in 6NTS
Label Count Molecule
Proteins (3 molecules)
1
Serine/threonine-protein Phosphatase 2A 65 KDA Regulatory Subunit a Alpha Isoform
(Gene symbol: PPP2R1A)
Molecule annotation
1
Serine/threonine-protein Phosphatase 2A 56 KDA Regulatory Subunit Alpha Isoform
(Gene symbol: PPP2R5A)
Molecule annotation
1
Serine/threonine-protein Phosphatase 2A Catalytic Subunit Alpha Isoform
(Gene symbol: PPP2CA)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
N-[(1R,2R,3S)-2-hydroxy-3-(10H-phenoxazin-10-yl)cyclohexyl]-4-(trifluoromethoxy)benzene-1-sulfonamideN-[(1R,2R,3S)-2-hydroxy-3-(10H-phenoxazin-10-yl)cyclohexyl]-4-(trifluoromethoxy)benzene-1-sulfonamide
2
2
MANGANESE (II) IONMANGANESE (II) ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303