6PLF: Crystal structure of human PHGDH complexed with Compound 1

PDB ID: 6PLFDownload
MMDB ID: 177796
PDB Deposition Date: 2019/6/30
Updated in MMDB: 2019/09
Experimental Method:
x-ray diffraction
Resolution: 1.7  Å
Source Organism:
Similar Structures:
Biological Unit for 6PLF: dimeric; determined by author and by software (PISA)
Molecular Components in 6PLF
Label Count Molecule
Proteins (2 molecules)
2
D-3-phosphoglycerate Dehydrogenase
(Gene symbol: PHGDH)
Molecule annotation
Chemicals and Non-standard biopolymers (7 molecules)
1
2
4-{(1S)-1-[(5-chloro-6-{[(5S)-2-oxo-1,3-oxazolidin-5-yl]methoxy}-1H-indole-2-carbonyl)amino]-2-hydroxyethyl}benzoic acid4-{(1S)-1-[(5-chloro-6-{[(5S)-2-oxo-1,3-oxazolidin-5-yl]methoxy}-1H-indole-2-carbonyl)amino]-2-hydroxyethyl}benzoic acid
2
5
1,2-ETHANEDIOL1,2-ETHANEDIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303