6QEI: CRYSTAL STRUCTURE OF HUMAN METHIONINE AMINOPEPTIDASE-2 IN COMPLEX WITH AN INHIBITOR 5,6-Difluoro-3-(2-isopropoxy-4-piperazin-1-yl-phenyl)-1H-indole-2-carboxylic acid amide

PDB ID: 6QEIDownload
MMDB ID: 174968
PDB Deposition Date: 2019/1/7
Updated in MMDB: 2019/06
Experimental Method:
x-ray diffraction
Resolution: 1.8  Å
Source Organism:
Similar Structures:
Biological Unit for 6QEI: monomeric; determined by author and by software (PISA)
Molecular Components in 6QEI
Label Count Molecule
Protein (1 molecule)
1
Methionine Aminopeptidase 2
(Gene symbol: METAP2)
Molecule annotation
Chemicals and Non-standard biopolymers (7 molecules)
1
2
1,2-ETHANEDIOL1,2-ETHANEDIOL
2
1
GLYCEROLGLYCEROL
3
1
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
4
1
5,6-bis(fluoranyl)-3-(4-piperazin-1-yl-2-propan-2-yloxy-phenyl)-1~{H}-indole-2-carboxamide5,6-bis(fluoranyl)-3-(4-piperazin-1-yl-2-propan-2-yloxy-phenyl)-1~{H}-indole-2-carboxamide
5
2
MANGANESE (II) IONMANGANESE (II) ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303