6S79: Crystal structure of CARM1 in complex with inhibitor AA183

PDB ID: 6S79Download
MMDB ID: 184875
PDB Deposition Date: 2019/7/4
Updated in MMDB: 2024/05
Experimental Method:
x-ray diffraction
Resolution: 2.1  Å
Source Organism:
Similar Structures:
Biological Unit for 6S79: dimeric; determined by author and by software (PISA)
Molecular Components in 6S79
Label Count Molecule
Proteins (2 molecules)
2
Histone-arginine Methyltransferase Carm1
(Gene symbol: CARM1)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
2
(2~{S})-4-[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl-[3-(pyridin-2-ylamino)propyl]amino]-2-azanyl-butanoic acid(2~{S})-4-[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl-[3-(pyridin-2-ylamino)propyl]amino]-2-azanyl-butanoic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303