6SB0: cryo-EM structure of mTORC1 bound to PRAS40-fused active RagA/C GTPases

PDB ID: 6SB0Download
MMDB ID: 180543
PDB Deposition Date: 2019/7/18
Updated in MMDB: 2019/10
Experimental Method:
electron microscopy
Resolution: 5.5  Å
Source Organism:
Similar Structures:
Biological Unit for 6SB0: dodecameric; determined by author
Molecular Components in 6SB0
Label Count Molecule
Proteins (12 molecules)
2
Mtor,serine/threonine-protein Kinase Mtor,mtor,serine/threonine-protein Kinase Mtor
(Gene symbol: MTOR)
Molecule annotation
2
Target of Rapamycin Complex Subunit Lst8
(Gene symbol: MLST8)
Molecule annotation
2
Ras-related Gtp-binding Protein a
(Gene symbol: RRAGA)
Molecule annotation
2
Ras-related Gtp-binding Protein C
(Gene symbol: RRAGC)
Molecule annotation
2
Regulatory-associated Protein of Mtor
(Gene symbol: RPTOR)
Molecule annotation
2
Proline-rich Akt1 Substrate 1
(Gene symbol: AKT1S1)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
2
GUANOSINE-5'-TRIPHOSPHATEGUANOSINE-5'-TRIPHOSPHATE
2
2
GUANOSINE-5'-DIPHOSPHATEGUANOSINE-5'-DIPHOSPHATE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303