6TDE: Tubulin-inhibitor complex

PDB ID: 6TDEDownload
MMDB ID: 191890
PDB Deposition Date: 2019/11/8
Updated in MMDB: 2020/09
Experimental Method:
x-ray diffraction
Resolution: 2.286  Å
Source Organism:
Rattus norvegicus▼
Similar Structures:
Biological Unit for 6TDE: pentameric; determined by author and by software (PISA)
Molecular Components in 6TDE
Label Count Molecule
Proteins (5 molecules)
2
Tubulin Alpha Chain
Molecule annotation
2
Tubulin Beta Chain
Molecule annotation
1
Stathmin-4
Molecule annotation
Chemicals and Non-standard biopolymers (17 molecules)
1
9
SULFATE IONSULFATE ION
2
2
GUANOSINE-5'-TRIPHOSPHATEGUANOSINE-5'-TRIPHOSPHATE
3
2
MAGNESIUM IONMAGNESIUM ION
4
2
GUANOSINE-5'-DIPHOSPHATEGUANOSINE-5'-DIPHOSPHATE
5
2
~{N}-[(10~{S})-3,4,5-trimethoxy-16-methylidene-14-oxatetracyclo[9.7.0.0^{2,7}.0^{13,17}]octadeca-1(18),2,4,6,11,13(17)-hexaen-10-yl]ethanamide~{N}-[(10~{S})-3,4,5-trimethoxy-16-methylidene-14-oxatetracyclo[9.7.0.0^{2,7}.0^{13,17}]octadeca-1(18),2,4,6,11,13(17)-hexaen-10-yl]ethanamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303