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6V5B:
Human Drosha and DGCR8 in complex with Primary MicroRNA (MP/RNA complex) - Active state
PDB ID:
6V5B
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MMDB ID:
186151
PDB Deposition Date:
2019/12/4
Updated in MMDB:
2020/05
Experimental Method:
electron microscopy
Resolution:
3.7 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
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Biological Unit for 6V5B: tetrameric; determined by author
Molecular Components in 6V5B
Label
Count
Molecule
Proteins (3 molecules)
A
1
Ribonuclease 3
(Gene symbol:
DROSHA
)
C
B
2
Microprocessor Complex Subunit Dgcr8
(Gene symbol:
DGCR8
)
Nucleotide(1 molecule)
D
1
Pri-mir-16-2 (78-mer)
Chemicals and Non-standard biopolymers (3 molecules)
1
2
ZINC ION
2
1
CALCIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303