National Center for
Biotechnology Information

6WM2: Human V-ATPase in state 1 with SidK and ADP

PDB ID:

6WM2 Download

MMDB ID:

195076

PDB Deposition Date:

2020/4/20

Updated in MMDB:

2020/12

Experimental Method:

electron microscopy

Resolution:

3.1 Å

Source Organism:

Homo sapiens▼

Taxonomy	Molecule
Homo sapiens	H, I, J, K, L, M, O, P, R, A, B, C, D, E, F, G, N, 0, 1, 2, 3, 4, 5, 6, 7, 8, 9, Q, S, T, U, V
Legionella pneumophila	X, Y, Z

Similar Structures:

Biological Unit for 6WM2: 35-meric; determined by author

Molecular Components in 6WM2
Label	Count	Molecule
Proteins (35 molecules)
H I J	3	V-type Proton Atpase Subunit E 1
K L M	3	V-type Proton Atpase Subunit G 1
O	1	V-type Proton Atpase Subunit C 1
P	1	V-type Proton Atpase Subunit H
R	1	V-type Proton Atpase 116 KDA Subunit a Isoform 1
A B C	3	V-type Proton Atpase Catalytic Subunit a
D E F	3	V-type Proton Atpase Subunit B, Brain Isoform
X Y Z	3	Sidk
G	1	V-type Proton Atpase Subunit D
N	1	V-type Proton Atpase Subunit F
0	1	V-type Proton Atpase 21 KDA Proteolipid Subunit
1 2 3 4 5 6 7 8 9	9	V-type Proton Atpase 16 KDA Proteolipid Subunit
Q	1	V-type Proton Atpase Subunit D 1
S	1	V-type Proton Atpase Subunit E 1
T	1	Ribonuclease Kappa
U	1	V-type Proton Atpase Subunit S1
V	1	Renin Receptor
Chemicals and Non-standard biopolymers (63 molecules)
1	1	beta-D-glucopyranose (Link to PubChem not yet available)
2	4	beta-D-galactopyranose (Link to PubChem not yet available)
3	2	2-acetamido-2-deoxy-beta-D-galactopyranose (Link to PubChem not yet available)
4	2	N-acetyl-alpha-neuraminic acid (Link to PubChem not yet available)
5	14	2-acetamido-2-deoxy-beta-D-glucopyranose (Link to PubChem not yet available)
6	1	beta-D-mannopyranose (Link to PubChem not yet available)
7	5	alpha-D-mannopyranose (Link to PubChem not yet available)
8	3	alpha-D-glucopyranose (Link to PubChem not yet available)
9	4	CHOLESTEROL (Link to PubChem not yet available)
10	1	1,2-DICAPROYL-SN-PHOSPHATIDYL-L-SERINE (Link to PubChem not yet available)
11	13	PHOSPHATIDYLETHANOLAMINE (Link to PubChem not yet available)
12	10	tri(methyl)-[2-[[(2~{R})-2-[(~{Z})-octadec-9-enoyl]oxy-3-[(~{E})-1-oxidanylideneoctadec-9-enoxy]propoxy]-oxidanyl-phosphoryl]oxyethyl]azanium (Link to PubChem not yet available)
13	1	methyl (3R,6Z,10E,14E)-3,7,11,15,19-pentamethylicosa-6,10,14,18-tetraen-1-yl dihydrogen diphosphate (Link to PubChem not yet available)
14	1	ADENOSINE-5'-DIPHOSPHATE (Link to PubChem not yet available)
15	1	(2~{S})-2-$l^{4}-azanyl-3-[[(2~{R})-3-octadecanoyloxy-2-oxidanyl-propoxy]-oxidanyl-oxidanylidene-$l^{6}-phosphanyl]oxy-propanoic acid (Link to PubChem not yet available) $(2~{S})-2-$l^{4}-azanyl-3-[[(2~{R})-3-octadecanoyloxy-2-oxidanyl-propoxy]-oxidanyl-oxidanylidene-$l^{6}-phosphanyl]oxy-propanoic acid$

* Click molecule labels to explore molecular sequence information.

Citing MMDB

Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303