6YEN: Crystal structure of AmpC from E. coli with Taniborbactam (VNRX-5133)

PDB ID: 6YENDownload
MMDB ID: 189329
PDB Deposition Date: 2020/3/25
Updated in MMDB: 2024/10
Experimental Method:
x-ray diffraction
Resolution: 1.418  Å
Source Organism:
Similar Structures:
Biological Unit for 6YEN: monomeric; determined by author and by software (PISA)
Molecular Components in 6YEN
Label Count Molecule
Protein (1 molecule)
1
Beta-lactamase
(Gene symbol: ampC)
Molecule annotation
Chemicals and Non-standard biopolymers (13 molecules)
1
1
(3~{R})-3-[2-[4-(2-azanylethylamino)cyclohexyl]ethanoylamino]-2-oxidanyl-3,4-dihydro-1,2-benzoxaborinine-8-carboxylic acid(3~{R})-3-[2-[4-(2-azanylethylamino)cyclohexyl]ethanoylamino]-2-oxidanyl-3,4-dihydro-1,2-benzoxaborinine-8-carboxylic acid
2
1
2-(N-MORPHOLINO)-ETHANESULFONIC ACID2-(N-MORPHOLINO)-ETHANESULFONIC ACID
3
1
DI(HYDROXYETHYL)ETHERDI(HYDROXYETHYL)ETHER
4
3
1,2-ETHANEDIOL1,2-ETHANEDIOL
5
1
(10aR)-2-(((1r,4R)-4-((2-aminoethyl)amino)cyclohexyl)methyl)-6-carboxy-4-hydroxy-4,10a-dihydro-10H-benzo[5,6][1,2]oxaborinino[2,3-b][1,4,2]oxazaborol-4-uide(10aR)-2-(((1r,4R)-4-((2-aminoethyl)amino)cyclohexyl)methyl)-6-carboxy-4-hydroxy-4,10a-dihydro-10H-benzo[5,6][1,2]oxaborinino[2,3-b][1,4,2]oxazaborol-4-uide
6
2
ZINC IONZINC ION
7
3
CHLORIDE IONCHLORIDE ION
8
1
SODIUM IONSODIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303