7JFR: Auristatin bound to tubulin

PDB ID: 7JFRDownload
MMDB ID: 192524
PDB Deposition Date: 2020/7/17
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 2.35  Å
Source Organism:
Rattus norvegicus▼
Similar Structures:
Biological Unit for 7JFR: heptameric; determined by author
Molecular Components in 7JFR
Label Count Molecule
Proteins (6 molecules)
2
Tubulin Alpha-1b Chain
Molecule annotation
2
Tubulin Beta-2b Chain
Molecule annotation
1
Stathmin-4
Molecule annotation
1
Uncharacterized Protein
Molecule annotation
Chemicals and Non-standard biopolymers (12 molecules)
L
1
Auristatin
1
2
GUANOSINE-5'-TRIPHOSPHATEGUANOSINE-5'-TRIPHOSPHATE
2
5
MAGNESIUM IONMAGNESIUM ION
3
1
CALCIUM IONCALCIUM ION
4
2
GUANOSINE-5'-DIPHOSPHATEGUANOSINE-5'-DIPHOSPHATE
5
1
PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTERPHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303