7L5E: Crystal Structure of KPT-330 bound to CRM1 (537-DLTVK-541 to GLCEQ)

PDB ID: 7L5EDownload
MMDB ID: 198092
PDB Deposition Date: 2020/12/21
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 1.944  Å
Source Organism:
Homo sapiens▼
Similar Structures:
Biological Unit for 7L5E: trimeric; determined by author and by software (PISA)
Molecular Components in 7L5E
Label Count Molecule
Proteins (3 molecules)
1
Gtp-binding Nuclear Protein RAN
Molecule annotation
1
Ran-specific Gtpase-activating Protein 1
Molecule annotation
1
Exportin-1
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
1
PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTERPHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER
2
1
MAGNESIUM IONMAGNESIUM ION
3
1
GLYCEROLGLYCEROL
4
1
selinexor, bound formselinexor, bound form
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303