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7LIA:
5-HT bound serotonin transporter reconstituted in lipid nanodisc in presence of NaCl in outward facing conformation
PDB ID:
7LIA
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MMDB ID:
209869
PDB Deposition Date:
2021/1/26
Updated in MMDB:
2021/12
Experimental Method:
electron microscopy
Resolution:
3.3 Å
Source Organism:
Mus musculus
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Taxonomy
Molecule
Mus musculus
B, C
Homo sapiens
A
Similar Structures:
VAST+
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Biological Unit for 7LIA: trimeric; determined by author
Molecular Components in 7LIA
Label
Count
Molecule
Proteins (3 molecules)
A
1
Sodium-dependent Serotonin Transporter
B
1
Variable Domain of 15b8 Antibody FAB Heavy Chain
C
1
Variable Domain of 15b8 Antibody FAB Light Chain
Chemicals and Non-standard biopolymers (27 molecules)
1
2
2-acetamido-2-deoxy-beta-D-glucopyranose
2
2
SEROTONIN
3
1
CHLORIDE ION
4
2
SODIUM ION
5
5
DECANE
6
13
HEPTANE
7
1
PENTANE
8
1
CHOLESTEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303