7LWD: Cryo-EM structure of the wild-type human serotonin transporter complexed with vilazodone, imipramine and 15B8 Fab

PDB ID: 7LWDDownload
MMDB ID: 205520
PDB Deposition Date: 2021/3/1
Updated in MMDB: 2024/10
Experimental Method:
electron microscopy
Resolution: 3.65  Å
Source Organism:
Mus musculus▼
Similar Structures:
Biological Unit for 7LWD: trimeric; determined by author
Molecular Components in 7LWD
Label Count Molecule
Proteins (3 molecules)
1
Sodium-dependent Serotonin Transporter
Molecule annotation
1
Heavy Chain Antibody Fragment
Molecule annotation
1
Light Chain Antibody Fragment
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
3-(5H-DIBENZO[B,F]AZEPIN-5-YL)-N,N-DIMETHYLPROPAN-1-AMINE3-(5H-DIBENZO[B,F]AZEPIN-5-YL)-N,N-DIMETHYLPROPAN-1-AMINE
2
1
5-{4-[4-(5-cyano-1H-indol-3-yl)butyl]piperazin-1-yl}-1-benzofuran-2-carboxamide5-{4-[4-(5-cyano-1H-indol-3-yl)butyl]piperazin-1-yl}-1-benzofuran-2-carboxamide
3
1
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303