8FCE: HIV-1 Reverse Transcriptase in complex with 7-membered bicyclic core NNRTI

PDB ID: 8FCEDownload
MMDB ID: 226256
PDB Deposition Date: 2022/12/1
Updated in MMDB: 2024/05
Experimental Method:
x-ray diffraction
Resolution: 2.77  Å
Source Organism:
Similar Structures:
Biological Unit for 8FCE: dimeric; determined by author and by software (PISA)
Molecular Components in 8FCE
Label Count Molecule
Proteins (2 molecules)
1
P66 RT
Molecule annotation
1
P51 RT
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
4-[(9-{4-[(E)-2-cyanoethenyl]-2,6-dimethylphenyl}-6-oxo-6,7,8,9-tetrahydro-5H-pyrimido[4,5-b][1,4]diazepin-2-yl)amino]benzonitrile4-[(9-{4-[(E)-2-cyanoethenyl]-2,6-dimethylphenyl}-6-oxo-6,7,8,9-tetrahydro-5H-pyrimido[4,5-b][1,4]diazepin-2-yl)amino]benzonitrile
2
1
L(+)-TARTARIC ACIDL(+)-TARTARIC ACID
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303