8RCK: CryoEM structure of mTORC1 with a paediatric kidney cancer-associated 1455-EWED-1458 duplication in mTOR, Focused on one protomer copy

PDB ID: 8RCKDownload
MMDB ID: 252074
PDB Deposition Date: 2023/12/6
Updated in MMDB: 2024/09
Experimental Method:
electron microscopy
Resolution: 3.4  Å
Source Organism:
Similar Structures:
Biological Unit for 8RCK: tetrameric; determined by author and by software
Molecular Components in 8RCK
Label Count Molecule
Proteins (4 molecules)
1
Serine/threonine-protein Kinase Mtor
(Gene symbol: MTOR)
Molecule annotation
1
Target of Rapamycin Complex Subunit Lst8
(Gene symbol: MLST8)
Molecule annotation
1
Regulatory-associated Protein of Mtor
(Gene symbol: RPTOR)
Molecule annotation
1
Eukaryotic Translation Initiation Factor 4e-binding Protein 1
(Gene symbol: EIF4EBP1)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTERPHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
2
2
MAGNESIUM IONMAGNESIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303