8RO2: Integrative Structure of the human intron lariat Spliceosome (ILS'')

PDB ID: 8RO2Download
MMDB ID: 252435
PDB Deposition Date: 2024/1/11
Updated in MMDB: 2024/10
Experimental Method:
electron microscopy
Resolution: 3.5  Å
Source Organism:
Similar Structures:
Biological Unit for 8RO2: 40-meric; determined by author and by software
Molecular Components in 8RO2
Label Count Molecule
Proteins (36 molecules)
1
116 KDA U5 Small Nuclear Ribonucleoprotein Component
Molecule annotation
1
Pre-mrna-splicing Factor Isy1 Homolog
Molecule annotation
1
Atp-dependent RNA Helicase Dhx15
Molecule annotation
1
U5 Small Nuclear Ribonucleoprotein 40 KDA Protein
Molecule annotation
1
Crooked Neck-like Protein 1
Molecule annotation
1
Pre-mrna-splicing Factor Spf27
Molecule annotation
1
Cwf19-like Protein 1
Molecule annotation
1
Protein Bud31 Homolog
Molecule annotation
1
Pre-mrna-splicing Factor Rbm22
Molecule annotation
1
Intron-binding Protein Aquarius
Molecule annotation
1
SNW Domain-containing Protein 1
Molecule annotation
1
Peptidyl-prolyl Cis-trans Isomerase-like 1
Molecule annotation
1
Pre-mrna-processing Factor 17
Molecule annotation
1
Coiled-coil Domain-containing Protein 12
Molecule annotation
1
Small Nuclear Ribonucleoprotein SM D3
Molecule annotation
1
Small Nuclear Ribonucleoprotein SM D1
Molecule annotation
1
Small Nuclear Ribonucleoprotein SM D2
Molecule annotation
1
Small Nuclear Ribonucleoprotein E
Molecule annotation
1
Small Nuclear Ribonucleoprotein F
Molecule annotation
1
Small Nuclear Ribonucleoprotein G
Molecule annotation
4
Pre-mrna-processing Factor 19
Molecule annotation
1
Splicing Regulator Sde2
Molecule annotation
1
Splicing Factor Ess-2 Homolog
Molecule annotation
1
Pre-mrna-processing-splicing Factor 8
Molecule annotation
1
Pre-mrna-splicing Factor Syf1
Molecule annotation
1
Cell Division Cycle 5-like Protein
Molecule annotation
1
Cwf19-like Protein 2
Molecule annotation
1
Pre-mrna-splicing Factor Syf2
Molecule annotation
1
Spliceosome-associated Protein Cwc15 Homolog
Molecule annotation
1
Pax3- and Pax7-binding Protein 1
Molecule annotation
1
Pleiotropic Regulator 1
Molecule annotation
1
Tuftelin-interacting Protein 11
Molecule annotation
1
Small Nuclear Ribonucleoprotein-associated Proteins B and B'
Molecule annotation
Nucleotides(4 molecules)
1
U2 Snrna
Molecule annotation
1
U6 Snrna
Molecule annotation
1
U5 Snrna
Molecule annotation
1
Intron
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
3
1
* Click molecule labels to explore molecular sequence information.

Citing MMDB