8TOL: nhTMEM16 lipid scramblase in lipid nanodiscs with MSP1E3 scaffold protein in the presence of Ca2+ (open state)

PDB ID: 8TOLDownload
MMDB ID: 246540
PDB Deposition Date: 2023/8/3
Updated in MMDB: 2024/11
Experimental Method:
electron microscopy
Resolution: 2.85  Å
Source Organism:
Similar Structures:
Biological Unit for 8TOL: dimeric; determined by author
Molecular Components in 8TOL
Label Count Molecule
Proteins (2 molecules)
2
Lipid Scramblase Nhtmem16
(Gene symbol: NECHADRAFT_66456)
Molecule annotation
Chemicals and Non-standard biopolymers (16 molecules)
1
4
CALCIUM IONCALCIUM ION
2
12
(1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate(1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303