National Center for
Biotechnology Information

8YN3: Cryo-EM structure of histamine H2 receptor in complex with histamine and miniGs

PDB ID:

MMDB ID:

253327

PDB Deposition Date:

2024/3/10

Updated in MMDB:

2024/10

Experimental Method:

electron microscopy

Resolution:

2.56 Å

Source Organism:

synthetic construct▼

Taxonomy	Molecule
synthetic construct	A, N
Homo sapiens	B, C, R

Similar Structures:

Biological Unit for 8YN3: pentameric; determined by author

Molecular Components in 8YN3
Label	Count	Molecule
Proteins (5 molecules)
A	1	Engineered Guanine Nucleotide,binding Protein G(s) Subunit Alpha
B	1	Guanine Nucleotide-binding Protein G(i)/g(s)/g(t) Subunit Beta-1
C	1	Guanine Nucleotide-binding Protein G(i)/g(s)/g(o) Subunit Gamma-2
N	1	Nanobody Nb35
R	1	Histamine H2 Receptor
Chemicals and Non-standard biopolymers (2 molecules)
1	1	HISTAMINE
2	1	CHOLESTEROL

* Click molecule labels to explore molecular sequence information.

Citing MMDB