VAST+ is a tool designed to identify macromolecules that have similar 3-dimensional structures, with an emphasis on finding those with similar biological assemblies ("biological units" or "biounits"). The similarities are calculated using purely geometric criteria, and therefore can identify distant homologs that cannot be recognized by sequence comparison.

To use VAST+, enter the PDB ID or MMDB ID of any structure that is currently in the Molecular Modeling Database (MMDB). VAST+ will display a list of similar structures, ranking them by the extent of their similarity to the query structure's biological unit. more...