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Accession: PRJNA278887 ID: 278887

Homo sapiens (human)

BT474 48h Lapatinib+JQ1 transcriptome response

See Genome Information for Homo sapiens
This experiment evaluated the transcriptome response of the SKBR3 HER2-positive breast cancer cell line to 48 hours treatment with 300nM lapatinib, 300nM JQ1, or the combination treatment, relative to a DMSO-only control.
AccessionPRJNA278887
Data TypeTranscriptome or Gene expression
ScopeMonoisolate
OrganismHomo sapiens[Taxonomy ID: 9606]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens
Grants
  • "Whole Kinome Profiling and Remodeling in HER2+ Breast Cancer" (Grant ID IIR12-225201, Susan G. Komen Foundation)
  • "Activation and Regulation of the Understudied Kinome Using MIB/MS Technology" (Grant ID U01 MH104999, NIH National Institute of Mental Health)
  • "Kinome Reprogramming in Response to Targeted Kinase Inhibitors" (Grant ID R01 GM101141, NIH National Institute of General Medical Sciences)
  • "Basic Mechanisms of Viral and Chemical Carcinogenesis" (Grant ID T32 CA009156, NIH National Cancer Institute)
SubmissionRegistration date: 19-Mar-2015
University of North Carolina at Chapel Hill
RelevanceMedical
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments7
Other datasets
BioSample7
SRA Data Details
ParameterValue
Data volume, Gbases10
Data volume, Mbytes4728

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