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Accession: PRJNA826456 ID: 826456

Effects of CDK8/19 mediator kinase inhibition by Senexin B in HAP-1 cells treated with or without interferon-gamma (human)

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This project is a component of the Transcriptomic and Proteomic Effects of CDK8 and CDK19 Mediator Kinases
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5 additional projects are components of the Transcriptomic and Proteomic Effects of CDK8 and CDK19 Mediator Kinases.
98285 additional projects are related by organism.
RNA-Seq analysis was carried out to investigate the effects of selective CDK8/19 inhibitor Senexin B on gene transcription mediated by IFN-gamma signaling pathway in HAP-1 cells. More...
AccessionPRJNA826456; GEO: GSE200735
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismHomo sapiens[Taxonomy ID: 9606]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens
PublicationsChen M et al., "CDK8 and CDK19: positive regulators of signal-induced transcription and negative regulators of Mediator complex proteins.", Nucleic Acids Res, 2023 Aug 11;51(14):7288-7313
SubmissionRegistration date: 13-Apr-2022
College of Pharmacy, University of South Carolina
RelevanceMedical
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments12
Publications
PubMed1
PMC1
Other datasets
BioSample12
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Supplementary Mbytes6
SRA Data Details
ParameterValue
Data volume, Gbases56
Data volume, Mbytes29665

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