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Accession: PRJNA514343 ID: 514343

Gene expression profiling of alveolar macrophages from normal lung and metastasis-associated macrophages (house mouse)

See Genome Information for Mus musculus
To profile the gene expression of macrophages associated with lung metastases and identify mechanisms by which macrophages regulate metasetatic growth Overall design: Lung metastases were induced by tail vein injection of syngenic mouse mammary tumor cells, dissected and processed in parallel with normal lungs for FACS sorting for the CD11B+ and CD11C+ subsets of CD45+;F4/80+;LY6C-;MRC1+;FSC hi cells. RNA from these cells was analyzed by RNA-seq.
AccessionPRJNA514343; GEO: GSE124933
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismMus musculus[Taxonomy ID: 10090]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus; Mus musculus
PublicationsZheng W et al., "Induction of interferon signaling and allograft inflammatory factor 1 in macrophages in a mouse model of breast cancer metastases.", Wellcome Open Res, 2021;6:52
SubmissionRegistration date: 10-Jan-2019
Genetics, Yale School of Medicine
RelevanceModel Organism
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments10
Publications
PubMed1
PMC1
Other datasets
BioSample11
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Supplementary Mbytes2
SRA Data Details
ParameterValue
Data volume, Gbases143
Data volume, Mbytes21132

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