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Genome Information for Mus musculus
To profile the gene expression of macrophages associated with lung metastases and identify mechanisms by which macrophages regulate metasetatic growth
Overall design: Lung metastases were induced by tail vein injection of syngenic mouse mammary tumor cells, dissected and processed in parallel with normal lungs for FACS sorting for the CD11B+ and CD11C+ subsets of CD45+;F4/80+;LY6C-;MRC1+;FSC hi cells. RNA from these cells was analyzed by RNA-seq.
Accession | PRJNA514343; GEO: GSE124933 |
Data Type | Transcriptome or Gene expression |
Scope | Multiisolate |
Organism | Mus musculus[Taxonomy ID: 10090] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus; Mus musculus |
Publications | Zheng W et al., "Induction of interferon signaling and allograft inflammatory factor 1 in macrophages in a mouse model of breast cancer metastases.", Wellcome Open Res, 2021;6:52 |
Submission | Registration date: 10-Jan-2019 Genetics, Yale School of Medicine |
Relevance | Model Organism |
Project Data:
Resource Name | Number of Links |
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Sequence data |
SRA Experiments | 10 |
Publications |
PubMed | 1 |
PMC | 1 |
Other datasets |
BioSample | 11 |
GEO DataSets | 1 |