Mus musculus (ID 230476) - BioProject

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Accession: PRJNA230476 ID: 230476

Mus musculus (house mouse)

Targeting Csnk1a1 induces selective p53-dependant killing of leukemia stem cells

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71988 additional projects are related by organism.

We found found that casein kinase 1 alpha (Csnk1a1), a serine threonine kinase and negative regulator of beta catenin, is essential for leukemia cells in vivo. More...

Accession	PRJNA230476; GEO: GSE52928
Data Type	Transcriptome or Gene expression
Scope	Multiisolate
Organism	Mus musculus[Taxonomy ID: 10090] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus; Mus musculus
Publications	Järås M et al., "Csnk1a1 inhibition has p53-dependent therapeutic efficacy in acute myeloid leukemia.", J Exp Med, 2014 Apr 7;211(4):605-12
Submission	Registration date: 3-Dec-2013 Cancer program, Broad Institute of MIT and Harvard
Relevance	Model Organism

Project Data:

Resource Name	Number of Links
Publications
PubMed	1
PMC	1
Other datasets
GEO DataSets	2

GEO Data Details

Parameter	Value
Data volume, Spots	407529
Data volume, Processed Mbytes	14
Data volume, Supplementary Mbytes	3

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Mus musculus (house mouse)

Targeting Csnk1a1 induces selective p53-dependant killing of leukemia stem cells

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