In an on-going Microbial Observatory study on the International Space Station, multiple bacterial isolates of Biosafety Level 2 (BSL-2) were isolated and identified. The antibiotic susceptibility pattern was tested in these BSL-2 isolates for the following antibiotics: cefazolin, ciprofloxacin, cefoxitin, erythromycin, gentamycin, oxacillin, penicillin, rifampin, tobramycin and many of the BSL-2 isolates showed multiple drug resistance. Among these isolates, 21 strains were chosen for whole genome sequencing. The genomic data can enable to determine the influence of microgravity on the pathogenicity and virulence in the BSL-2 microorganisms.
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