BioProject

Collection of plasmids and other isolates from Firmicutes. The aim of this effort was to expand the understanding of horizontal gene transfer in Staphylococcus aureus, a major primary pathogen in community and hospital settings by sequencing 100 distinct large, conjugative plasmids from key groups of staphylococci. More...

Collection of plasmids and other isolates from Firmicutes. The aim of this effort was to expand the understanding of horizontal gene transfer in Staphylococcus aureus, a major primary pathogen in community and hospital settings by sequencing 100 distinct large, conjugative plasmids from key groups of staphylococci. Of particular interest, is the emerging phenomenon of community-acquired-methicillin-resistant S. aureus (CA-MRSA) a cause of life-threatening infections in otherwise healthy adults. Plasmid DNA was isolated using selective approaches, samples were prepared using a high-throughput library preparation process, sequenced and then assembled using a plasmid specific assembly pipeline. Less...