See
Genome Information for Homo sapiens
The major histocompatibility complex (MHC) region on chromosome 6 (6p21.13) includes many genes and haplotype variations that significantly impact autoimmunity and infectious response. More...
The major histocompatibility complex (MHC) region on chromosome 6 (6p21.13) includes many genes and haplotype variations that significantly impact autoimmunity and infectious response. The MHC region is gene-dense and highly polymorphic, including variation at the level of gene content. Susceptibility to over 100 diseases has been associated with this region.
The MHC Haplotype Project is sequencing the 4.5Mb MHC region for at least 8 common haplotypes. Comparison of the genomic sequence will increase our understanding of variations in this critical region of the genome. This project provides an important public resource in terms of clones, sequence, and variation data and provides framework for association studies of MHC-linked diseases. Less...
| Accession | PRJNA13671 |
| Data Type | Targeted Locus (Loci) |
| Scope | Multiisolate |
| Organism | Homo sapiens[Taxonomy ID: 9606] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens |
| Publications (total 3) Less... | - Stewart CA et al., "Complete MHC haplotype sequencing for common disease gene mapping.", Genome Res, 2004 Jun;14(6):1176-87
More...- Stewart CA et al., "Complete MHC haplotype sequencing for common disease gene mapping.", Genome Res, 2004 Jun;14(6):1176-87
- Horton R et al., "Gene map of the extended human MHC.", Nat Rev Genet, 2004 Dec;5(12):889-99
- Allcock RJ et al., "The MHC haplotype project: a resource for HLA-linked association studies.", Tissue Antigens, 2002 Jun;59(6):520-1
Less... |
| Submission | Registration date: 17-Mar-2005
Sanger Institute |
| Related Resources | |
Project Data:
| Resource Name | Number
of Links |
|---|
| Publications |
| PubMed | 3 |
| PMC | 1 |
No public data is linked to this project. Any recently released data that cites this project will be linked to it within a few days.