Mus musculus (ID 379364) - BioProject

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Accession: PRJNA379364 ID: 379364

Mus musculus (house mouse)

Temperature adaptation effects on BAT metabolism

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This project is a component of the Active brown fat engages fatty acid synthesis through AKT2 stimulated ChREBP activity, simultaneously with fatty acid oxidation, to maintain fuel storage

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1 additional project is a component of the Active brown fat engages fatty acid synthesis through AKT2 stimulated ChREBP activity, simultaneously with fatty acid oxidation, to maintain fuel storage.

72143 additional projects are related by organism.

We are reporting here the effects of adaptation to different ambient temperatures in the whole genome gene expression of interscapular BAT Overall design: B6/J mice were adapted to three different ambient temperatures (30ºC, 22ºC and 6ºC) for a period of 4 weeks.

Accession	PRJNA379364; GEO: GSE96680
Data Type	Transcriptome or Gene expression
Scope	Multiisolate
Organism	Mus musculus[Taxonomy ID: 10090] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus; Mus musculus
Publications	Sanchez-Gurmaches J et al., "Brown Fat AKT2 Is a Cold-Induced Kinase that Stimulates ChREBP-Mediated De Novo Lipogenesis to Optimize Fuel Storage and Thermogenesis.", Cell Metab, 2018 Jan 9;27(1):195-209.e6
Submission	Registration date: 16-Mar-2017 PMM Bioinformatics Core, Program in Molecular Medicine, University of Massachusetts
Relevance	Model Organism

Project Data:

Resource Name	Number of Links
Sequence data
SRA Experiments	12
Publications
PubMed	1
PMC	1
Other datasets
BioSample	12
GEO DataSets	1

GEO Data Details

Parameter	Value
Data volume, Supplementary Mbytes	1

SRA Data Details

Parameter	Value
Data volume, Gbases	27
Data volume, Mbytes	19161

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Mus musculus (house mouse)

Temperature adaptation effects on BAT metabolism

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