BioProject

Project data type: Raw sequence reads

Scope:

Multispecies

University of Lausanne

Project data type: Raw sequence reads

Scope:

Multispecies

Geisel School of Medicine at Dartmouth

Project data type: Raw sequence reads

Scope:

Multispecies

Shanghai Institute of Materia Medica, Chinese Academy of Sciences

Project data type: Raw sequence reads

Scope:

Multispecies

Shanghai Institute of Materia Medica, Chinese Academy of Sciences

Project data type: Raw sequence reads

Scope:

Multispecies

The Rockefeller University

Nosocomial pathogens serially passaged in silver nitrate (Raw sequence reads)

Project data type: Raw sequence reads

Scope:

Environment

University of Birmingham

Project data type: Raw sequence reads

Scope:

Multispecies

Uppsala University

Project data type: Other

Scope:

Monoisolate

European Bioinformatics Institute

Project data type: Raw sequence reads

Scope:

Multispecies

Washington University in St. Louis

Project data type: Raw sequence reads

Scope:

Multispecies

University of Rennes 1

Project data type: Raw sequence reads

Scope:

Multispecies

University of Warwick

Taxonomy:

Staphylococcus aureus subsp. aureus str. Newman

Project data type: Transcriptome or Gene expression

Scope:

Multiisolate

Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center

Taxonomy:

Staphylococcus aureus subsp. aureus str. Newman

Project data type: Transcriptome or Gene expression

Scope:

Multiisolate

Genomic Research Lab, Service of Infectious Diseases, Genomic Research Laboratory

This study describes the target receptor and mechanism of action of Staphylococcal superantigen like 13 (SSL13), a secret protein reside on S.aureus immune evasion cluster 2(IEC-2) that previously supposed to modulate immune evasion. In sharp contrast to the characterized SSLs located on the staphylococcal pathogenicity island 2 (SPI-2) , that inhibit immune functions, We demonstrate SSL13 is a chemoattractant and a neutrophil activator that acts via the FPR2. Therefore, SSL13 is a unique SSL member not belonging to the immune evasion class, but is a pathogen alarming molecule sensed by the FPR2. Our study provides a new conception of SSLs, that not only inhibit host immune processes but also recruit human neutrophils to the site of infection, where S. aureus can be disarmed by secreted immune evasion proteins and used as vesicles to other parts of the host. This allow us to better understand of S. aureus pathological processes.

Project data type: Other

Scope:

Monoisolate

UMC Utrecht

Project data type: Other

Scope:

Monoisolate

European Bioinformatics Institute

Staphylococcus aureus subsp. aureus transcriptional response to sunlight in oxic and anoxic conditions

Taxonomy:

Staphylococcus aureus subsp. aureus str. Newman

Project data type: Transcriptome or Gene expression

Scope:

Monoisolate

Stanford University

Staphylococcus aureus subsp. aureus str. Newman Genome sequencing and assembly

Taxonomy:

Staphylococcus aureus subsp. aureus str. Newman

Project data type: Genome sequencing and assembly

Scope:

Multiisolate

NYU Langone Health

Project data type: Other

Scope:

Monoisolate

European Bioinformatics Institute

RNA-Seq-mediated transcriptome analysis of Staphylococcus aureus Newman wild-type, walKD119A, walKV149A and DHBP-treated wild-type strains

Taxonomy:

Staphylococcus aureus subsp. aureus str. Newman

Project data type: Transcriptome or Gene expression

Scope:

Multiisolate

Chemistry, UChicago

Transcriptomic profiling of BRC+, BRC-, DRC+ and DRC- FACS-sorted samples

Taxonomy:

Staphylococcus aureus subsp. aureus str. Newman

Project data type: Transcriptome or Gene expression

Scope:

Multiisolate

Core Unit Systems Medicine, Medical Department, University of Würzburg