BioSample

The rodent malaria parasite Plasmodium yoelii is an important animal model for studying host-parasite interaction and molecular basis of malaria pathogenesis. Although a draft genome of P. yoelii has been published, and assembled chromosomes are available publicly, errors in gene model prediction still exist. With the advances in DNA sequencing technologies and reduction in sequencing costs, genome-wide RNA sequencing (RNA-seq) has become an effective approach to study gene expression and gene expression regulation. Additionally, cDNA sequences can provide experimental information to confirm or correct errors in the predicted gene models based on genome sequence.