BSN138

Identifiers: BioSample: SAMN38637717; Sample name: Staphylococcus aureus str BSN138; SRA: SRS20598164

Organism: Staphylococcus aureus
cellular organisms; Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Staphylococcaceae; Staphylococcus

Attributes

strain	BSN138
collected by	Andrew D. Berti
collection date	2021-10-04
geographic location	USA: Detroit, MI
host	Homo sapiens
host disease	central line-associated bloodstream infection
isolation source	blood
latitude and longitude	42.33 N 83.05 W
genotype	ST8-MRSA-IVa CC8
host age	53
host description	Patient with end-stage renal disease on hemodialysis presents with septic shock related to her tunneled hemodialysis line which was removed. Clinical course was complicated by encephalopathy, acute hypoxic respiratory failure and upper gastrointestinal bleeding. Medical management consisted of vancomycin with cefepime, ceftriaxone, ampicillin and acyclovir added for empiric meningitis coverage. While hopsitalized, the patient developed a myocardial infarction refractory to cardiac revascularization. In the setting of unstable, refractory ventricular arrhythmias on maximum pressor support, the patient's code status was changed and she expired. Duration of bacteremia: 4 days.
host disease outcome	death
host sex	female
host subject id	BSS138
methicillin susceptibility	resistant
Ridom spa type	t024
Kreiswirth spa type	YGFMBQBLO
Alternate Nomenclature	B0799
Other Isolates from Patient	none
Provenance	Detroit Medical Center > Berti

BioProject: PRJNA1048360 Staphylococcus aureus
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Antibiogram
Antibiotic	Resistance phenotype	Measurement sign	Measurement	Measurement units	Laboratory typing method	Laboratory typing platform	Vendor	Laboratory typing method version or reagent	Testing standard
clindamycin	susceptible	<=	0.5	mg/L	MIC	Phoenix	Becton Dickinson		CLSI
daptomycin	susceptible	<=	1	mg/L	MIC	Phoenix	Becton Dickinson		CLSI
erythromycin	resistant	>	4	mg/L	MIC	Phoenix	Becton Dickinson		CLSI
gentamicin	susceptible	<=	1	mg/L	MIC	Phoenix	Becton Dickinson		CLSI
linezolid	susceptible	==	2	mg/L	MIC	Phoenix	Becton Dickinson		CLSI
oxacillin	resistant	>	2	mg/L	MIC	Phoenix	Becton Dickinson		CLSI
rifampin	susceptible	<=	0.5	mg/L	MIC	Phoenix	Becton Dickinson		CLSI
trimethoprim-sulfamethoxazole	susceptible	<=	0.5/9.5	mg/L	MIC	Phoenix	Becton Dickinson		CLSI
vancomycin	susceptible	==	1	mg/L	MIC	Phoenix	Becton Dickinson		CLSI
vancomycin	susceptible	==	2	mg/L	MIC		Biomérieux	E-Test	CLSI

BioSample