| broad-scale environmental context | Human digestive system |
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| collection date | 2019-07-03 |
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| environmental medium | faeces |
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| geographic location | USA |
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| investigation type | metagenome-assembled genome |
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| isolation source | human feces metagenome |
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| project name | Despite the emerging success of immunotherapy in non-small-cell lung cancer (NSCLC), it re-mains clinically important to better identify patients who are likely to respond to treatment, espe-cially considering the existence of immune-related adverse events (irAEs). In recent years, the gut microbiome has been correlated with treatment response, but no predictive models relating the two have been developed. Findings from our current study showed that a functional profile of the human gut microbiome outperformed taxonomical results across different studies and can be uti-lized to establish a model with good predictive value in lung cancer immunotherapy. |
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| sample name | SRR20881984_bin.4_MetaWRAP_v1.3_MAG |
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| ENA-CHECKLIST | ERC000047 |
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| ENA-FIRST-PUBLIC | 2023-07-18T12:24:28Z |
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| ENA-LAST-UPDATE | 2023-07-18T12:24:28Z |
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| External Id | SAMEA114095826 |
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| INSDC center alias | EMG |
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| INSDC center name | EMG |
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| INSDC first public | 2023-07-18T12:24:28Z |
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| INSDC last update | 2023-07-18T12:24:28Z |
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| INSDC status | public |
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| Submitter Id | SRR20881984_bin.4_MetaWRAP_v1.3_MAG |
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| assembly quality | Many fragments with little to no review of assembly other than reporting of standard assembly statistics |
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| assembly software | metaspades v3.15.3 |
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| binning parameters | MaxBin2, MetaBat2, Concoct with default parameter of the metaWRAP pipeline. Bin refinement module used from metaWRAP with default parameters. |
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| binning software | MetaWRAP v1.3 |
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| broker name | EMG broker account, EMBL-EBI |
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| completeness score | 94.93 |
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| completeness software | CheckM |
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| contamination score | 0.6 |
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| geographic location (latitude) | 41.65966 |
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| geographic location (longitude) | -91.54766 |
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| local environmental context | colon |
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| metagenomic source | human feces metagenome |
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| sample derived from | SAMN30170373 |
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| scientific_name | Acidaminococcus fermentans |
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| sequencing method | Illumina HiSeq 4000 |
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| taxonomic classification | The taxonomy of this Metagenome-Assembled Genome was originally computed with GTDBtk, which assigned the following taxonomic annotation: d__Bacteria;p__Firmicutes;c__Negativicutes;o__Acidaminococcales;f__Acidaminococcaceae;g__Acidaminococcus;s__Acidaminococcus fermentans |
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| taxonomic identity marker | multi-marker approach |
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