FIGURE 11.2.. Glycosphingolipid (GSL) neutral cores and their designation based on IUPAC (International Union of Pure and Applied Chemistry) Nomenclature.

FIGURE 11.2.

Glycosphingolipid (GSL) neutral cores and their designation based on IUPAC (International Union of Pure and Applied Chemistry) Nomenclature. In the official nomenclature, saccharide and other substituents that extend or branch from the neutral core structures are indicated by a roman numeral designating which of the neutral core sugars (counting the sugar closest to the ceramide as “I”) carries the substituent, and a superscript designating which hydroxyl on that sugar is modified. For example, see ganglioside GT1b (IV3Neu5AcII3[Neu5Ac]2Gg4Cer) in Figure 11.1. See Online Appendix 1B for full names and designated symbols for monosaccharides.

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From: Chapter 11, Glycosphingolipids

Cover of Essentials of Glycobiology
Essentials of Glycobiology [Internet]. 4th edition.
Varki A, Cummings RD, Esko JD, et al., editors.
Cold Spring Harbor (NY): Cold Spring Harbor Laboratory Press; 2022.
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