Line graphs showing decreases in G B M thickness, T B M thickness, mesangial fractional volume, and mesangial matrix fractional volume 10 years after pancreas transplantation

FIGURE 30.

Renal Histologic Changes at Baseline and 5 and 10 Years After Pancreas Transplantation.

Thickness of the GBM (Panel A), thickness of the TBM (Panel B), mesangial fractional volume (Panel C), and mesangial matrix fractional volume (Panel D) are shown before (baseline) and after pancreas transplantation in persons with type 1 diabetes. Shaded areas represent the normal ranges obtained in 66 age- and sex-matched normal controls (mean ± 2 standard deviations). GBM, glomerular basement membrane; Mes, mesangium; MM, mesangial matrix; TBM, tubular basement membrane; Vv, fractional volume.

SOURCE: Reference (369), copyright © 2012 Springer, reprinted with permission.

From: Kidney Disease and Diabetes

Cover of Diabetes in America
Diabetes in America [Internet].
Lawrence JM, Casagrande SS, Herman WH, et al., editors.
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