Table 1PICO characteristics of review question

Population

Adults receiving iodine-based contrast media

Strata:

  • Intravenous vs intra-arterial media administration
Exclusion:
  • High osmolar contrast media

Risk toolValidated risk assessment tools/questionnaires for acute kidney injury
Patient outcomes

Diagnosis of an acute kidney injury using any study definition

Timeframe:

  • Within 7 days of contrast administration

Statistical outcomes

Primary outcomes:

  • Sensitivity and specificity
  • Positive and negative predictive values
  • Positive and negative likelihood ratios
  • Area under the receiver operator curve (AUC)
    • Had to report variance.
Calibration (Hosmer-Lemeshow test)

Minimal important difference (MID):

  • Sensitivity: upper= 80%, lower= 60%
  • Specificity: upper= 90%, lower= 80%
  • AUC: upper= 0.70, lower= 0.50
  • Hosmer-Lemeshow: p value >0.05
Secondary Outcomes (include only if reported in papers reporting primary outcomes):
  • Mortality (risk ratio, odds ratio or hazard ratio)
  • Dialysis (risk ratio, odds ratio or hazard ratio)

Study design
  • Prospective cohort studies
  • Systematic reviews of prognostic cohort studies

From: Evidence review for risk prediction tools and eGFR for the prediction of iodine-based contrast media-associated acute kidney injury

Cover of Evidence review for risk prediction tools and eGFR for the prediction of iodine-based contrast media-associated acute kidney injury
Evidence review for risk prediction tools and eGFR for the prediction of iodine-based contrast media-associated acute kidney injury: Acute Kidney Injury (update): Evidence review B.
NICE Guideline, No. 148.
Copyright © NICE 2024.

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