This Consensus Study Report was reviewed in draft form by individuals chosen for their diverse perspectives and technical expertise. The purpose of this independent review is to provide candid and critical comments that will assist the National Academies of Sciences, Engineering, and Medicine in making each published report as sound as possible and to ensure that it meets the institutional standards for quality, objectivity, evidence, and responsiveness to the study charge. The review comments and draft manuscript remain confidential to protect the integrity of the deliberative process.

We thank the following individuals for their review of this report:

• ANNE E. BURKE, Johns Hopkins University School of Medicine
• HERMINE I. BRUNNER, Cincinnati Children’s Hospital Medical Center
• DAVID A. HAFLER, Yale University
• JUDITH A. JAMES, Oklahoma Medical Research Foundation, University of Oklahoma Health Sciences Center
• SUE JINKS-ROBERTSON, Duke University
• FREDERICK W. MILLER, National Institutes of Health
• GARY W. MILLER, Columbia University Mailman School of Public Health
• DAVID S. PISETSKY, Duke University & Durham VA Medical Center
• D. BRENT POLK, University of California San Diego
• MARIAN REWERS, Barbara Davis Center for Diabetes, University of Colorado School of Medicine
• TERRY J. SMITH, University of Michigan Medical School
• ROBERT B. WALLACE, The University of Iowa

Although the reviewers listed above provided many constructive comments and suggestions, they were not asked to endorse the conclusions or recommendations of this report nor did they see the final draft before its release. The review of this report was overseen by BETTY A. DIAMOND, The Feinstein Institute for Medical Research, and ALAN I. LESHNER, American Association for the Advancement of Science (AAAS). They were responsible for making certain that an independent examination of this report was carried out in accordance with the standards of the National Academies and that all review comments were carefully considered. Responsibility for the final content rests entirely with the authoring committee and the National Academies.