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National Clinical Guideline Centre (UK). Care of Dying Adults in the Last Days of Life. London: National Institute for Health and Care Excellence (NICE); 2015 Dec 16. (NICE Guideline, No. 31.)

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Care of Dying Adults in the Last Days of Life.

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Appendix NUnit Costs

DrugPreparationUnits/packCost/packCost/unit(a)Usual 24 hour doseCost/daySource(b)
Alfentanil1 mg/2 ml solution for injection ampoules10£3.50£0.350.5-no max£0.35eMIT109
Atropine600 micrograms/1 ml solution for injection ampoules10£11.70£1.170.4mg£1.17NHS Drug Tariff,
December 2014347
Buprenorphine10 micrograms/hour transdermal patches4£31.56£7.89Changed every 7 days£1.12NHS Drug Tariff,
March 2015348
Buprenorphine200 microgram sublingual tablets sugar free50£5.04£0.10800-1200mcg£0.80 - £1.20NHS Drug Tariff,
March 2015348
Clonazepam1mg/ml injection ampoules1£6.00£6.001-8mg (depending on indication)£6.00 - £48.00Palliative Care Formulary (PCF5)441
Clonazepam2 mg tablets100£8.97£0.090.5mg£0.09NHS Drug Tariff,
March 2015348
Cyclizine50 mg tablets100£11.26£0.11150 mg£0.33NHS Drug Tariff,
December 2014347
Cyclizine50 mg/1 ml solution for injection ampoules5£8.65£1.73150mg£5.19NHS Drug Tariff,
December 2014347
Dexamethasone2mg/5ml oral solution sugar free150ml£42.30£0.284mg£2.82NHS Drug Tariff,
March 2015348
Dexamethasone4mg/ml ampoules for injectionNANA£1.992-16mg£1.98 - £7.96BNF 2015246
Dexamethasone2 mg tablets50£49.45£0.994mg£1.98NHS Drug Tariff,
December 2014347
Dexamethasone500 micrograms tablets28£60.50£2.164mg£17.28NHS Drug Tariff,
December 2014347
Diamorphine10 mg powder for solution for injection ampoules5£14.05£2.815 - no max dose£2.81NHS Drug Tariff,
March 2015348
Diazepam5 mg/2.5 ml rectal solution tube5£7.35£1.475-30mg£1.47 - £8.82NHS Drug Tariff,
March 2015348
Diclofenac100mg suppositories10£3.03£0.30100 mg£0.30NHS Drug Tariff,
March 2015348
Diclofenac75 mg/3 ml solution for injection ampoules10£8.26£0.83100 – 150 mg£0.83 - £1.66NHS Drug Tariff,
March 2015348
Domperidone10 mg tablets30£2.06£0.0730mg£0.21NHS Drug Tariff,
December 2014347
Domperidone10 mg tablets100£6.87£0.0730mg£0.21NHS Drug Tariff,
December 2014347
Domperidone5 mg/5 ml oral suspension 200 ml200£13.32£0.0730mg£2.00NHS Drug Tariff,
December 2014347
Fentanyl100 microgram buccal tablets sugar free28£139.42£4.99Variable 100-800mcg£4.99 - £39.92NHS Drug Tariff,
March 2015348
Fentanyl25 micrograms/hour transdermal patches5£18.00£3.601 patch every 3 days£1.20NHS Drug Tariff,
March 2015348
Fosaprepitant150 mg per vial powder for reconstitution (vial)1£47.42£47.42150mg£47.42BNF December 2014246
Furosemide10mg/ml ampoules for injectionNANA£0.50 per 2ml ampoules40-160mg£1.00 - £4.00Palliative Care Formulary (PCF5)441
Glycopyrronium bromide0.2 mg/mL solution for injection ampoules3ml£1.50£0.500.6 mg£1.50BNF December 2014246
Granisetron3.1mg/24 hours patches1£56.00£56.001 patch for 5 days£11.20BNF December 2014246
Granisetron hydrochloride1mg/mL solution for injection ampoules3£2.40£0.809 mg£7.20BNF December 2014246
Haloperidol5 mg/1 ml solution for injection ampoules5£1.82£0.361.5mg£0.36NHS Drug Tariff,
March 2015348
Haloperidol500microgram capsules30£1.18£0.041.5mg£0.12NHS Drug Tariff,
March 2015348
Haloperidol1.5 mg tablets28£2.50£0.091.5mg£0.09NHS Drug Tariff,
December 2014347
Haloperidol5 mg/5 ml oral solution100£6.41£0.061.5mg£0.09NHS Drug Tariff,
December 2014347
Hydromorphone10mg/ml ampoules for injectionNANA£9.002mg – no max£9.00Palliative Care Formulary (PCF5)441
Hyoscine butylbromide20 mg/1 ml solution for injection ampoules10£2.92£0.2960mg£0.87NHS Drug Tariff,
December 2014347
Hyoscine hydrobromide400 micrograms/1 ml solution for injection ampoules10£30.513.050.4mg£3.05NHS Drug Tariff,
December 2014347
Ketorolac30 mg/1 ml solution for injection ampoules6£3.99£0.6760-90mg£1.34 - £2.01eMIT109
Levomepromazine25 mg/1 ml solution for injection ampoules10£20.13£2.016mg£2.01NHS Drug Tariff,
March 2015348
Lorazepam1 mg tablets sublingual28£2.52£0.090.5-4mg£0.09 - £0.36NHS Drug Tariff,
March 2015348
Metoclopramide10 mg tablets28£0.97£0.0330mg£0.09NHS Drug Tariff,
December 2014347
Metoclopramide10 mg/2 ml solution for injection ampoules10£3.15£0.3230mg£1.92NHS Drug Tariff,
December 2014347
Metoclopramide5 mg/5 ml oral solution 150 ml150£19.60£0.1330mg£3.90NHS Drug Tariff,
December 2014347
Midazolam10 mg/2 ml solution for injection ampoules10£1.60£0.1610-60mg (but can be higher)£0.16eMIT109
Midazolam2.5 mg/0.5 ml oromucosal solution pre-filled oral syringes4£82.00£20.5010-30mg£82.00 - £230.00NHS Drug Tariff,
March 2015348
Morphine sulfate10 mg/1 ml solution for injection ampoules10£9.36£0.0910mg – no max dose£0.09NHS Drug Tariff,
March 2015348
Morphine sulfate10mg/5ml oral solution300ml£5.45£5.4510mg – no max dose£0.09NHS Drug Tariff,
March 2015348
Octreotide500 micrograms/1 ml solution for injection ampoules5£135.47£27.090.25mg£54.18NHS Drug Tariff,
December 2014347
Olanzapine2.5 mg orodispersible tablets28£1.12£0.042.5-10mg£0.04 - £0.16NHS Drug Tariff,
March 2015348
Olanzapine10 mg orodispersible tablets28£3.43£0.122.5-10mg£0.12NHS Drug Tariff,
December 2014347
Olanzapine5 mg orodispersible tablets28£2.73£0.102.5-10mg£0.10NHS Drug Tariff,
December 2014347
Olanzapine5 mg orodispersible tablets28£3.66£0.132.5-10mg£0.13NHS Drug Tariff,
December 2014347
Ondansetron8 mg 0rodispersible tablets10£80.26£8.038mg£8.03NHS Drug Tariff,
December 2014347
Oxycodone10 mg/1ml solution for injection ampoules5£8.00£1.605-no max dose£1.60NHS Drug Tariff,
March 2015348
Oxycodone10 mg/ml oral solution sugar free120ml£46.63£0.3910- no max dose£0.39 - maximum dose givenNHS Drug Tariff,
March 2015348
Oxycodone50mg/1ml solution for injection ampoules5£70.01£14.015-no max dose£14.01 - maximum dose givenNHS Drug Tariff,
March 2015348
Palonosetron0.05 mg/ml solution for injection ampoules5£55.89£11.180.25mg£55.90BNF December 2014246
Prochlorperazine12.5 mg/1 ml solution for injection ampoules10£5.23£0.522.5mg£0.52NHS Drug Tariff,
December 2014347
Prochlorperazine3 mg tablets28£1.03£0.046mg£0.08NHS Drug Tariff,
December 2014347
Prochlorperazine5 mg/5 ml oral solution100£3.34£0.035mg£0.15NHS Drug Tariff,
December 2014347
a

Cost per unit for oral solutions is presented as £ per ml.

b

Cost sources are given as they were when presented to the Committee.

Copyright © 2015 National Clinical Guideline Centre.
Bookshelf ID: NBK356019

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