Table 13Summary of studies included in the review

StudyPopulationAnalysisPrognostic/diagnostic variable(s)Outcomes
Chiang 2009 (and Kao 2009 - age ≥65 subgroup)21,52Prospective cohort
n=729

People with terminal cancer admitted to a palliative care unit.

Taiwan, China
Multivariate analysis
(logistic regression)
Cognitive status, edema, jaundice, ECOG score, ascitesMortality at 7 days (adjusted OR)
Escalante 200033Retrospective cohort
n=122

People with cancer presenting to an emergency department with acute dyspnoea as a primary or secondary complaint.

USA
Multivariate analysis
(logistic regression)
Triage blood pressure, respiration, pulse, response to treatment, history if metastasis, cancer diagnosisMortality at 14 days (adjusted OR)
Hui 2014B47Prospective cohort
n=357
People with terminal cancer admitted to a palliative care unit

USA and Brazil
Diagnostic performance of signs and symptomsApnea periods, Cheyne-Stokes breathing, death rattle, dysphagia of liquids, decreased level of consciousness, sedation, Palliative Performance Scale, peripheral cyanosis, pulselessness of radial artery, respiration with mandibular movement and urine output.Mortality at 3 days
Loekito 2013A61Retrospective cohort
n=42701

People admitted to hospital for more than 24 hours.

Australia
Diagnostic performance of signs and symptomsHaemoglobin, haematocrit, total bicarbonate, white cell count, albumin, pH, bilirubin, creatinine, urea.Mortality at 2 days
Loekito 201362Retrospective cohort
n=71453

People in the emergency department

Australia
Diagnostic performance of signs and symptomsHaemoglobin, haematocrit, total bicarbonate, white cell count, albumin, pH, bilirubin, creatinine, urea.Mortality at 2 days
Matsunuma 201465Retrospective cohort
n=93

People with terminal lung cancer admitted to a palliative care unit

Japan
Multivariate analysis (Cox proportional hazards regression)Anorexia, fatigue, hyponatremia, hypoalbuminemiaMortality at 14 days (adjusted HR)

From: 5, Recognising when a person may be in the last days of life

Cover of Care of Dying Adults in the Last Days of Life
Care of Dying Adults in the Last Days of Life.
NICE Guideline, No. 31.
National Clinical Guideline Centre (UK).
Copyright © 2015 National Clinical Guideline Centre.

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