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Guidelines for Diagnosing and Managing Disseminated Histoplasmosis among People Living with HIV [Internet]. Washington (DC): Pan American Health Organization; 2020 Apr.

Cover of Guidelines for Diagnosing and Managing Disseminated Histoplasmosis among People Living with HIV

Guidelines for Diagnosing and Managing Disseminated Histoplasmosis among People Living with HIV [Internet].

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ANNEX 4DIAGNOSTIC TESTS FOR HISTOPLASMOSIS

Company/productAntigen
IMMY/Clarus Histoplasma GM Enzyme Immunoassay (Ref. HGM201)

Commercial: CE label. Detection of antigens in urine.

Research use only in the United States. United States Food and Drug Administration clearance underway.

https://www​.immy.com/hgm

MiraVista/Polyclonal Ab ELISA

(CPT code: 87385)

In-house: Indianapolis, IN, USA. Detection of antigens in urine, sera, and other body fluids. In the process of commercialization.

https:​//miravistalabs​.com/medical-fungal-infection-testing​/antigen-detection​/histoplasma-quantitative-eia-test

Molecular

HOLOGIC/AccuProbe Histoplasma capsulatum culture identification test

(Ref. 102910)

In situ hybridization assay for identification of H. capsulatum isolated from culture
Culture

Abbott/ISOLATOR™

(Ref. 50C7)

Commercial: Lysis centrifugation system https://www​.alere.com​/en/home/product-details​/isolator-10ml-microbial-tubes.html
BD/BACTEC™ Myco/F Lytic (Ref. 442288) Commercial: CE label. Lysis system, automatic incubation system http://legacy​.bd.com​/ds/technicalCenter/inserts​/PP162JAA(05).pdf
Antibody

IMMY/Immunodiffusion Fungal Antibody Test Kit

(Ref. ID1001)

Commercial: CE label

http://www​.immy.com/products​/immunodiffusion-reagents-and-plates​/#1473453177095-9d6fbd00-fc50

Meridian/Immunodiffusion reagents

(Ref: 100201 and 100601)

Commercial: approved by the United States Food and Drug Administration

https://www​.meridianbioscience​.com/human-condition​/other/fungals​/histoplasma-antigen-for-fungal-immunodiffusion

IMMY/Complement Fixation Reagents

(Ref. H10150, H20110, H30150 and H40110)

Commercial: CE and in vitro diagnostic label

http://www​.immy.com/complement-fixation-reagents​/#1473453809831-e685dea0-e154

IMMY. LA-Histoplasma

(Ref. HL1001)

Commercial: approved by the United States Food and Drug Administration and CE label. https://www​.immy.com/latex
Gibson Bioscience. Fungal serology.

Commercial: The ATCC Licensed Derivative Emblem.

http://www​.gibsonbioscience​.com/GB-Products/Fungal-Serology/

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Bookshelf ID: NBK587196

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