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WHO recommendation: Calcium supplementation during pregnancy for the prevention of pre-eclampsia and its complications. Geneva: World Health Organization; 2018.

Cover of WHO recommendation: Calcium supplementation during pregnancy for the prevention of pre-eclampsia and its complications

WHO recommendation: Calcium supplementation during pregnancy for the prevention of pre-eclampsia and its complications.

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Annex 2Priority outcomes for decision-making

Key questionsPriority Outcomes
In pregnant women (P), does calcium supplementation (I) compared to placebo or no calcium supplementation (C), improve maternal and perinatal outcomes (O), including the onset of pre-eclampsia?
If so, in what populations of pregnant women or contexts is calcium supplementation most beneficial?
If so, what dosing regimen of calcium supplementation is most beneficial?
Maternal outcomes
  • Maternal death
  • Eclampsia
  • Pre-eclampsia
  • Recurrent seizures
  • Severe maternal morbidity
  • Maternal death or severe maternal morbidity
  • ICU admission
  • Adverse effects of interventions
Fetal/neonatal outcomes
  • Perinatal death
  • Admission to neonatal intensive care unit (NICU)/special nursery
  • Apgar scores
© World Health Organization 2018.

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Bookshelf ID: NBK535810

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