Annex 6Summary of NUGAG members' considerations for determining the strength of the recommendation
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| Quality of evidence: |
The quality of the evidence was considered sufficient to support a recommendation in all settings, including areas of malaria transmission High value was placed on the successful implementation of pilot programmes in both children and menstruating women in some countries
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| Values and preferences: |
Intermittent use of iron supplements can increase adherence as it might be easier for children and their caregivers to follow the intervention with less inconvenience The regular and less frequent provision of iron supplements could be a good preventive measure in public health programmes where daily iron supplementation regimens are non-existent or are not being successfully implemented at scale
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| Trade-off between benefits and harm: |
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| Cost and feasibility: |
This intervention is perceived as less costly compared with daily iron supplementation Implementation of intermittent supplementation may be particularly feasible in facilities such as schools, because supplements can be given throughout the school calendar year, reaching the target population with good acceptability. However, it is important that this intervention also reaches those children who are outside the school system This intervention should be considered in the context of all other options to improve iron nutrition
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