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BRCT: BRCA1 C Terminus (BRCT) domain
The BRCT domain is found predominantly in proteins involved in cell cycle checkpoint functions respo...
View in Cn3D Specific ProteinProteinSuperfamilySuperfamily MembersPubMed
BRCT_DNTT: BRCT domain of DNA nucleotidylexotransferase (DNTT) and similar proteins
DNTT (EC 2.7.7.31), also termed terminal addition enzyme, or terminal deoxynucleotidyltransferase, o...
BRCT_polymerase_mu: BRCT domain of DNA-directed DNA/RNA polymerase mu (polymerase mu) and similar proteins
Polymerase Mu (EC 2.7.7.7), also termed Pol mu, or terminal transferase, is a Gap-filling polymerase...
BRCT_MDC1_rpt2: second BRCT domain of mediator of DNA damage checkpoint protein 1 (MDC1) and similar proteins
MDC1, also termed nuclear factor with BRCT domains 1 (NFBD1), is a nuclear chromatin-associated prot...
BRCT_PAXIP1_rpt6: sixth BRCT domain of PAX-interacting protein 1 (PAXIP1) and similar proteins
PAXIP1, also termed PAX transactivation activation domain-interacting protein (PTIP), is involved in...
BRCT_BRC1_like_rpt6: sixth (C-terminal) BRCT domain of Schizosaccharomyces pombe BRCT-containing protein 1 (BRC1) and similar proteins
Schizosaccharomyces pombe BRC1 is required for mitotic fidelity, specifically in the G2 phase of the...
BRCT_BRC1_like_rpt4: fourth BRCT domain of Schizosaccharomyces pombe BRCT-containing protein 1 (BRC1) and similar proteins
BRCT_BRC1_like_rpt3: third BRCT domain of Schizosaccharomyces pombe BRCT-containing protein 1 (BRC1) and similar proteins
BRCT_BRC1_like_rpt2: second BRCT domain of Schizosaccharomyces pombe BRCT-containing protein 1 (BRC1) and similar proteins
BRCT_BRC1_like_rpt1: first (N-terminal) BRCT domain of Schizosaccharomyces pombe BRCT-containing protein 1 (BRC1) and similar proteins
BRCT_TopBP1_rpt5: fifth BRCT domain of DNA topoisomerase 2-binding protein 1 (TopBP1) and similar proteins
TopBP1, also termed DNA topoisomerase II-beta-binding protein 1, or DNA topoisomerase II-binding pro...
BRCT_Rad4_rpt3: third BRCT domain of Schizosaccharomyces pombe S-M checkpoint control protein Rad4 and similar proteins
Rad4, also termed P74, or protein cut5, is an essential component for DNA replication and the checkp...
BRCT_PAXIP1_rpt6_like: sixth BRCT domain of PAX-interacting protein 1 (PAXIP1), second BRCT domain of mediator of DNA damage checkpoint protein 1 (MDC1) and similar proteins
BRCT_DNA_ligase_III: BRCT domain of DNA ligase 3 (LIG3) and similar proteins
LIG3 (EC 6.5.1.1), also termed DNA ligase III, or polydeoxyribonucleotide synthase [ATP] 3, function...
BRCT_RFC1: BRCT domain of replication factor C subunit 1 (RFC1) and similar proteins
RFC1, also termed activator 1 140 kDa subunit, or A1 140 kDa subunit, or activator 1 large subunit, ...
BRCT_microcephalin_rpt3: third BRCT domain of microcephalin and similar proteins
Microcephalin is a DNA damage response protein involved in regulation of CHK1 and BRCA1. It has been...
BRCT_SLF1: BRCT domain of SMC5-SMC6 complex localization factor protein 1 (SLF1) and similar proteins
SLF1, also termed Smc5/6 localization factor 1, or ankyrin repeat domain-containing protein 32 (ANKR...
BRCT_TopBP1_rpt4: fourth BRCT domain of DNA topoisomerase 2-binding protein 1 (TopBP1) and similar proteins
TopBP1, also called DNA topoisomerase II-beta-binding protein 1, or DNA topoisomerase II-binding pro...
BRCT_DNA_ligase_like: BRCT domain of bacterial NAD-dependent DNA ligase (LigA) and similar proteins
LigA, also called NAD(+)-dependent polydeoxyribonucleotide synthase, catalyzes the formation of phos...
BRCT_PARP1: BRCT domain of poly [ADP-ribose] polymerase 1 (PARP-1) and similar proteins
PARP-1 (EC 2.4.2.30), also termed ADP-ribosyltransferase diphtheria toxin-like 1 (ARTD1), or NAD(+) ...
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