Conserved Protein Domain Family
RunxI
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pfam08504: RunxI 
Runx inhibition domain
This domain lies to the C-terminus of Runx-related transcription factors and homologous proteins (AML, CBF-alpha, PEBP2). Its function might be to interact with functional cofactors.
Links
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Statistics
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PSSM-Id: 430037
Aligned: 5 rows
Threshold Bit Score: 117.744
Created: 23-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
AMC39801      88 NQNQNSHFQTNSSPYhLYYGTGSGSYQFSMIptggsgSGSDRSPTRMLTSCTAAGgaagntGNNNLINANLGNQSDGVDA 167
XP_015201360 339 TQNQSGPFQTSSTPY-LYYGASSGSYQFSMV------PGGDRSPSRMLPPCTSAS------TGSSLINPNLPNQNDGVDA 405
XP_015676012  85 SQAQGSPFQTSSPSYhLYYGTSAGSYQFSMM------SGGDRSPPRILPPCTNAS------TGSTLLNPNLPNQNDVVDT 152
Q6YI83       386 PPRQLGNYSPGSPPYgIYHHLYGGSYQYPILpggsgtPQGPREPS-ILAATSNSQ------TQKPQLLPAQEKEASSQPG 458 Florida lancelet
XP_012902980 258 PQNQSGPFQANPSPYhLYYGASSGSYQFSMVags-ssSGGERSPTRMLASCTSSAs----vAAGNLMNPSLGGQSDSVEA 332

AMC39801     168 DGSHSNS------PTAMSASTRIDESVWRPY 192
XP_015201360 406 DGSHSSS------PTVLNSSGRMDESVWRPY 430
XP_015676012 153 EGSHSNS------PTNMGTTARLEEAVWRPY 177
Q6YI83       459 NGNHGNRqqdeqmDTQPGGSPEKRETVWRPY 489 Florida lancelet
XP_012902980 333 DGSHSNS------PTALSTPGRMDEAVWRPY 357
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