Conserved Protein Domain Family
ELYS

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pfam13934: ELYS 
Nuclear pore complex assembly
ELYS (embryonic large molecule derived from yolk sac) is conserved from fungi such Aspergillus nidulans and Schizosaccharomyces pombe to human. It is important for the assembly of the nuclear pore complex.
Statistics
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PSSM-Id: 464050
Aligned: 98 rows
Threshold Bit Score: 121.188
Created: 25-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_009401635         335 TLFIEDALSnlgieesyvqtgvevdisclqdDSsgllf-------lskidIAGGNGYPFRNLQAAADILFlrgtSd--MV 405 
EDO64220             697 LLFIDNYLEr--------------------eFDletvwka----whedspANSRSLYPPSSLQKALRILL----IpeaPL 748 
ETN65976             707 YLFIDNLLEr--------------------dFDpkairkvwvgssgkspaAAAVPLYPPKSLFKALRVML----LpevSL 762 
EDV99982             708 KLYIDEQLK----------------------RSgcaaa--------lkhnCQQEGLYPPQSMQALMRLIL----LptvSL 753 
WGS:AANI:GJ15958-PB  708 RLYIDEQLQhsgfk-------------vglqrQ-----------------SEQDGLYPPRTLQSLMRLML----LpdaKL 753 
WGS:AAPU:GI11104-PA  708 KLYIDELMR----------------------HYgfqae--------vqkqLKEDGLYPPQSLQTLMRLMM----LqdvSL 753 
WGS:AAQB:GK20017-PB  722 PLYIDTLLQqng-----------------lgnC-----------------MNDKQSYPPTTMKALMQMML----StdaQL 763 
XP_002027911         714 SLYIDRLLR----------------------RIsqe-----------sggVPVSLVYPPDT-QSIMNLML----SpntDM 755 
XP_001963471         703 KLYIDVLGMr----------------------------------------sGMTEAYPPDTLQSLLYLML----NpdtQT 738 
Q9VWE6               713 ILYIDSLGK----------------------R------------------ASFPEPYPPDSLHAYIHLML----SpdiEL 748  fruit fly
XP_009401635         406 VAKQAIFLYYLFD--------------Rhwkrp-daewkHivDDFAISFGIATHTVQESLVFYLLDDHTPqalQEAINLL 470 
EDO64220             749 ERKLVMLLYLFMDviaai-----ddddErfc-----ivaRqlEKFPRAFNVPIGLIERVRAFWHLDHGNV---SETVSEF 815 
ETN65976             763 ERKLVLLMYLFMDivai------hgdgRyrh------vlQrlEKFPQVFKLQLGLVRRVQAFWHLDHGNM---AWTVEEF 827 
EDV99982             754 LNKHELVLYLLHDldel-------vvvPqn-------ksTlaSDFATVFGIGVESVKRTRCFWFLDNDNI---KQAMKDF 816 
WGS:AANI:GJ15958-PB  754 DHKHELMLYVLHDvdq--------llvPkr-------krPlyQDFAMAFGIAEPLLKCARSFWFLDKGDY---EQTIDVL 815 
WGS:AAPU:GI11104-PA  754 EKKHELMLYVMLDldq--------fykSdk--------pElyNDFAMSFGLDEPLVKCVRSFWFLDKGDH---EMAIDVL 814 
WGS:AAQB:GK20017-PB  764 EQKHEVVLYLLMDldrinqgliveldkTkpplqekkmsmVlsKQFHIFFNLREEVIKSVQSFWHLDRGDY---WQAIDGL 840 
XP_002027911         756 DQKQEIILYLLLDldv---------hmPk---------vKlsSRFSTSFGLKKNLVLRVKSFWALDHDDH---SECIRLL 814 
XP_001963471         739 DRKYAIVLYFLMDlv----------------------apRqwVRFQGAFQISEQVVMSVRSFWFLDHGEF---DECVKEL 793 
Q9VWE6               749 CHKHALILYLLMDln-----------------------qQlvGRFQIAFQLDKDLATSLRCFWYLDHGDY---ERGVEEL 802  fruit fly
XP_009401635         471 --PEVAGpEIHP----KIAQVLLERQRADVALSILRCSGrdgglsnintdndfPqHEFLGEAitAVRVRIECGLLTEAFM 544 
EDO64220             816 lsPLSNAiEFPQwhreLAVSVLLRLDAPHLALKVLRAPG----------------APVAPQL--ELTTLVQNNLIPEAFS 877 
ETN65976             828 lsPLSCTvDFPQwhreLAVSVLLHQDASNLALKVLRAPG----------------SPVSPYL--ELLTLVRNNLISEAFS 889 
EDV99982             817 etG------YPDwqteLLVGVLLAQGAKKSAMHVMIRMS--------------V-DISSTEL--QLKVLLENNNIPKAFH 873 
WGS:AANI:GJ15958-PB  816 yrGRLGHsSYTEwqtkHLIETLLAHRANQEAMQVVHMPP----------------GFISSEL--KLQVLLANNNIPEAFH 877 
WGS:AAPU:GI11104-PA  815 yrGRTGHsVYTEwqtkHLIETLIRYNATPAAMQVVHLPP----------------GFISSEV--KLQVLLANNNIPEAFH 876 
WGS:AAQB:GK20017-PB  841 ydGIGKIrHYEDwqmkLIIENLLAANATRLAMRLVIRPP----------------GPVSFPL--YLRVLLANDRISEAFH 902 
XP_002027911         815 ssSKCSDnTYQNwhveLLVETLLAKGAITAAMSVVGRPP----------------GPLSTLT--HLKVLLASKNMPEAFD 876 
XP_001963471         794 ydSATPItGYEEwqskLLLETLLAAGASEAAMRVVSQPP----------------GPVDVWL--HLRVLLANDSIPEAFH 855 
Q9VWE6               803 ykEPAPAkNLKSwqmrLLIDKLLAEGAVKAAKKVVSRPP----------------GPLSSAL--HMKVLLANENITEAFQ 864  fruit fly
XP_009401635         545 FQRMQC---SKakdknlkykldigfsnssntefwiyltEVLVTEICHLCIR-RNLvDRMIEFPWNSDEEKHLHKCLFDH 619 
EDO64220             878 LQR-RTpqpDG----------------------------RQFVWFVEAIMMaGKP-ATLLEFALNDEEKYVLRSYLRDC 926 
ETN65976             890 VQR-RShqtDG----------------------------SQLICFVEAILSaGKA-ETLLEFSLTEEEKRVLREYLLDC 938 
EDV99982             874 LARSYM---DArg------------------------rQPFLEYVFNHCIStGKF-SVLNSLAMHETEEQLLYRLLRQS 924 
WGS:AANI:GJ15958-PB  878 HARIYM---DDdg-------------------------rPLLERFFRHCILnGKF-TVLATLCLREHEEQLVYRQLRQC 927 
WGS:AAPU:GI11104-PA  877 HARVYM---DDeg-------------------------rPLLERFFQHCIMeSKF-SVLATLCLRDNEEQLVYRQLRHC 926 
WGS:AAQB:GK20017-PB  903 YARLYD---DDkg-------------------------rPLLEHFFRHFINlGKF-KVLTELSLREDEEQLIYRLLRET 952 
XP_002027911         877 YARRND---DDvt------------------------grPLLEYFFRQCIEdRQF-KALAQLCLRESEEELALRLLREC 927 
XP_001963471         856 MARLYD---DEgg-------------------------yPLLERFFQHCIDhRRF-KVLAELCLREPEERLVYRLLRQC 905 
Q9VWE6               865 IARLDD---DEdg-------------------------qPLLERFFRHCIEiRRF-KVLAELYLREPEERLLYSLLRQC 914  fruit fly
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